Polynucleotide (PN) Treatment Singapore

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Polynucleotide (PN) treatment, such as Rejuran , Rejuran Healer or 婴儿针, is a skin healing and anti-aging treatment originated from South Korea. Polynucleotide (PN) is an enhanced version of Polydeoxyribonucleotide (PDRN). Due to its highly efficient skin healing and rejuvenation characteristics, it is frequently used as an skin repair and anti-ageing treatment.

Polynucleotide such as Rejuran improves the physiological conditions of your deep skin tissues, so your skin’s health can improve organically. This is accomplished by delivering Polynucleotide directly to the inner skin layer (dermis layer).

What is Polynucleotide (PN)?

A polynucleotide molecule is a biopolymer made up of 13 or more nucleotide monomers linked together by covalent bonds. Salmon DNA fragments are the main component, as it is thought to be compatible with human DNA.

The wound healing and anti-inflammatory function of PN makes it an ideal ingredient for skin repair and rejuvenation. Proven by numerous studies, PN helps with wound healing and skin repair. These compounds have been shown to trigger long-term skin regeneration from inside the inner skin layer. They work to enhance skin quality and health, and repair damage caused by damaging UV radiation, ageing and other environmental factors.

PN helps to maintain skin physiological function by assisting in the regeneration of various essential autologous components of the skin, such as glycosaminoglycan, proteins and glycoproteins.

Rejuran Singapore

Clinical Studies and Evidence

Polynucleotide is a skin treatment derived from salmon DNA that has been shown to promote skin healing, regeneration, and anti-aging effects. Several clinical studies have been conducted to support the efficacy of polynucleotide treatments.

Summary from some clinical studies on polynucleotides:

  • Collagen Stimulation: Polynucleotides promote the production of collagen and elastin, leading to firmer, more youthful skin.
  • Skin Repair and Healing: Polynucleotides derived from salmon DNA enhance wound healing, making it effective for treating scars, damaged skin, and improving overall skin health.
  • Anti-Aging Benefits: Polynucleotides significantly improve skin elasticity, hydration, and reduce wrinkles and fine lines.
  • Minimally Invasive: As a non-surgical option, Polynucleotides provide rejuvenation with minimal downtime and side effects.

Clinical trials and studies consistently show that Polynucleotides are effective in skin regeneration, anti-aging, acne scar treatment, and improving overall skin quality. Its ability to stimulate collagen production and accelerate skin healing makes it an effective treatment for individuals seeking non-surgical skin rejuvenation.

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Polynucleotide vs Skin Booster vs Skin Bio-Remodelling

Facts about various skin rejuvenation injectables treatments.

Treatment

Skin Bio-remodelling such as Profhilo

Skin Booster such as Teosyal Redensity I and Restylane skin booster

Polynucleotide such as Rejuran

Origin

Italy

Various countries

Korea

Content

High concentration Hyaluronic acid

Low concentration Hyaluronic acid

Polynucleotide (PN)

Injection technique

5-point injection on each side

Multiple micro injections

Multiple micro injections

Treatment regime 

2 treatments (1 month apart), followed by once every 6 months.

3-4 treatments (1 month apart), followed by once every 4-6 months

3-4 treatments (1 month apart), followed by once every 4-6 months

Benefits

Skin hydration

Skin lifting

Collagen and elastin

Skin hydration

Skin repair

Anti-inflammatory

Collagen

Pain level (0-10), based on patients’ feedback

6-7

3-5

Most skin boosters contain painkiller

6-8

Downtime

2-3 days

  

Cost

$$$

$$

$$

Indication

Dry skin

Skin sagging

Overall skin ageing

Dry skin

Damaged skin (acne, sun damage, ageing)

Who is Suitable for Having Polynucleotide Treatment?

Anyone who wishes to improve their face and neck skin quality are suitable to receive this treatment. In particular, individuals with damaged skin related to sun, ageing or acne and acne scars will benefit from this procedure.

Benefits of the Treatment

PN such as Rejuran offers numerous benefits for your skin.

  • Improves skin elasticity and texture 
  • Stimulates skin collagen production 
  • Improves sensitive skin
  • Improves inflammatory skin condition such as acne and eczema
  • Improves pores and acne scars
  • Balances oil and skin moisture
  • Improves fine lines and wrinkles
  • Increases thickness and density of the inner skin (dermis)
  • Improves overall skin health

Rejuran Singapore

Treatment Variants

Polynucleotides come in different viscosities:

  • The more viscous form of polynucleotides is more suitable for treating acne scars.
  • The less viscous form is generally used around thin skin areas, such as the eye area.
  • The choice of polynucleotides largely depends on the patient’s skin condition and expectations.

How Is The Treatment Done?

PN treatment takes approximately 15 to 30 minutes. Prior to the treatment, numbing cream is applied to minimize discomfort. PN is then being delivered with a series of tiny injections either with manual injection or machine injection.

Treatment regime is as such:

3 to 4 treatments (2-4 weeks between each treatment) initially, followed by one treatment every 3-4 months.

Downtime and Risks

PN is a skin-friendly product. Safety of the treatment is well established. 

You will have some needle marks, redness, and bruises just after treatment. These will resolve in about 2-3 days.

Long-term Effects and Maintenance

The long-term benefits of Polynucleotides include sustained improvements in skin texture, firmness, hydration, and resilience. By promoting collagen production and skin regeneration, it provides a natural, non-invasive option for combating the effects of aging and enhancing overall skin health.

Maintenance:

  • Maintain a good skincare routine.
  • Live a healthy lifestyle.
  • Avoid excessive sun exposure.
  • Treatment can be repeated once every 4 to 6 months to sustain long-term benefits.

Post-treatment Care

  • Avoid sun exposure, heat, and intense physical activity for a few days.
  • Keep the treated area clean, avoid touching it, and use gentle skincare.
  • Stay hydrated and avoid alcohol and smoking.
  • Monitor for side effects like swelling and bruising.
  • Be patient, as results become more apparent over time.

Combination Therapies

PN treatments can be combined with other aesthetic procedures for enhanced results, such as:

  • Hyaluronic acid skin booster
  • Hydrafacial
  • Digital Peel Laser
  • Pico laser

Regulatory Approval in Singapore

Polynucleotide (PN) treatments such as Rejuran are approved for use in Singapore. They are commonly used in licensed aesthetic clinics under the supervision of qualified healthcare professionals. While these treatments are not directly endorsed by specific health authorities, their regulatory approval ensures that they meet the required safety and efficacy standards for skin rejuvenation and anti-aging treatments.

Patients are encouraged to seek treatments only from accredited professionals to ensure optimal safety and results.

Polynucleotide Cost in Singapore

PN cost ranges from $300 – $800 in Singapore.

At SOL Aesthetics Medical Clinic, cost is $400 – $600. You may contact us for pricing details. 

Pre-treatment Consultation

We advise patients to have a diagnosis and consultaion session with our doctor before undergoing a this treatment. Our doctor will discuss in-depth regarding your skin condition and a suitable regime. 

You can make your appointment here.

*Disclaimer: The content provided is for educational and informational purposes only and does not intend to substitute professional medical advice, diagnosis, or treatment.

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